Article

Dynamic Transcriptome, Accessible Genome and PGR Cistrome Profiles in the Human Myometrium

2019-10-16

Abstract excerpt

The myometrium undergoes structural and functional remodeling during pregnancy. We hypothesize that myometrial genomic elements alter correspondingly in preparation for parturition. Human myometrial tissues from nonpregnant (NP) and term pregnant (TP) human subjects were examined by RNAseq, ATACseq and PGR ChIPseq assays to profile transcriptome, assessible genome and PGR occupancy. NP and TP specimens exhibit 289...

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Literature Corpus work: 1145936a-27d2-5f90-b942-2ce921ca14e2
DOI: 10.1101/806950

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