Article
Comprehensive analysis of genetic and evolutionary features of the hepatitis E virus.
BMC genomics - 29 Oct 2019
Baha Sarra, Behloul Nouredine, Liu Zhenzhen, Wei Wenjuan, Shi Ruihua, Meng Jihong
Abstract excerpt
BACKGROUND: The hepatitis E virus (HEV) is the causative pathogen of hepatitis E, a global public health concern. HEV comprises 8 genotypes with a wide host range and geographic distribution. This study aims to determine the genetic factors influencing the molecular adaptive changes of HEV open reading frames (ORFs) and estimate the HEV origin and evolutionary history. RESULTS: Sequences of HEV strains isolated...
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