Article
Genotype-Specific Evolution of Hepatitis E Virus.
Journal of virology - 1 May 2017
Brayne Adam B, Dearlove Bethany L, Lester James S, Kosakovsky Pond Sergei L, Frost Simon D W
Abstract excerpt
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis globally. HEV comprises four genotypes with different geographic distributions and host ranges. We utilize this natural case-control study for investigating the evolution of zoonotic viruses compared to single-host viruses, using 244 near-full-length HEV genomes. Genome-wide estimates of the ratio of nonsynonymous to synonymous evolutionary...
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