Article
Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana.
BMC infectious diseases - 28 Oct 2019
Acheampong Godfred, Owusu Michael, Owusu-Ofori Alex, Osei Isaac, Sarpong Nimako, Sylverken Augustina, Kung Hung-Jui, Cho Shu-Ting, Kuo Chih-Horng, Park Se Eun, Marks Florian, Adu-Sarkodie Yaw, Owusu-Dabo Ellis
Abstract excerpt
BACKGROUND: Salmonella infection poses significant public health threat globally, especially in resource-limited countries. Emergence and spread of antibiotic resistant strains to fluoroquinolones have led to treatment failures and increased mortality in Salmonella infection. However, there is dearth of information regarding mechanisms of resistance to fluoroquinolones in Ghana. This study therefore sought to...
Topics
- Adolescent
- Anti-Bacterial Agents
- Child, Preschool
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- Disk Diffusion Antimicrobial Tests
- Drug Resistance, Bacterial
- Female
- Fluoroquinolones
- Genes, Bacterial
- Ghana