Article
Comprehensive analysis of β-lactam resistant non-typhoidal Salmonella Isolates: Phenotypic and genotypic insights from clinical samples in Japan.
Journal of global antimicrobial resistance - 1 Jun 2025
Khalifa Hazim O, Kayama Shizuo, Ramadan Hazem, Yu Liansheng, Hayashi Wataru, Sugawara Yo, Kondo Sayaka Uchino, Marzooq Farah Al, Matsumoto Tetsuya, Sugai Motoyuki
Abstract excerpt
OBJECTIVE: This study examines β-lactam-resistant non-typhoidal Salmonella isolates using phenotypic and genotypic analyses to elucidate resistance mechanisms and epidemiological characteristics. METHODS: A total of 1663 clinical Salmonella spp. isolates were collected (1994-2016), with 122 exhibiting β-lactam resistance, confirmed via antimicrobial susceptibility testing. Resistance mechanisms were further...
Topics
- Humans
- Japan
- Salmonella
- Genotype
- Anti-Bacterial Agents
- Salmonella Infections
- Microbial Sensitivity Tests
- Phenotype
- Phylogeny
- beta-Lactam Resistance
- Whole Genome Sequencing
- beta-Lactams
- Drug Resistance, Multiple, Bacterial