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Comprehensive analysis of β-lactam resistant non-typhoidal Salmonella Isolates: Phenotypic and genotypic insights from clinical samples in Japan.

Journal of global antimicrobial resistance - 1 Jun 2025

Khalifa Hazim O, Kayama Shizuo, Ramadan Hazem, Yu Liansheng, Hayashi Wataru, Sugawara Yo, Kondo Sayaka Uchino, Marzooq Farah Al, Matsumoto Tetsuya, Sugai Motoyuki

Abstract excerpt

OBJECTIVE: This study examines β-lactam-resistant non-typhoidal Salmonella isolates using phenotypic and genotypic analyses to elucidate resistance mechanisms and epidemiological characteristics. METHODS: A total of 1663 clinical Salmonella spp. isolates were collected (1994-2016), with 122 exhibiting β-lactam resistance, confirmed via antimicrobial susceptibility testing. Resistance mechanisms were further...

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PMID: 40294860
DOI: 10.1016/j.jgar.2025.04.019

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