Autophagy induction can regulate skin pigmentation by causing melanosome degradation in keratinocytes and melanocytes

Abstract excerpt

Autophagy regulates cellular turnover by disassembling unnecessary or dysfunctional constituents. Recent studies demonstrated that autophagy and its regulators play a wide variety of roles in melanocyte biology. Activation of autophagy is known to induce melanogenesis and regulate melanosome biogenesis in melanocytes. Also, autophagy induction was reported to regulate physiologic skin color via melanosome...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy in Disease and Therapy
• Share to melanin and skin pigmentation
• Share to Sirtuins and Resveratrol in Medicine