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Article

Impact of Lysosomal Fraction on Melanin Synthesis Inhibition in a Zebrafish Melanogenesis Phenotype Model.

Molecular biotechnology - 1 Dec 2022

Jeon Gyeongchan, Kim Yang-Hoon, Min Jiho

Abstract excerpt

To develop whitening cosmetic materials, we conducted a study on lysosomes that decisively contribute to the decomposition of melanin during autophagy in keratinocytes. In this study, we found that the lysosomal fraction inhibits melanin synthesis in melanocyte, and the potential for the whitening function of lysosomal fraction to degrade melanin in the cells, or accompany other melanin synthesis inhibition...

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PMID: 35637367
DOI: 10.1007/s12033-022-00516-x

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