Article
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.
Experimental and molecular pathology - 1 Apr 2021
Cardoso Jéssica Vilarinho, Medeiros Rui, Dias Francisca, Costa Isabelle Alves, Ferrari Renato, Berardo Plinio Tostes, Perini Jamila Alessandra
Abstract excerpt
OBJECTIVE: DROSHA and DICER1 enzymes participate in the main stages of microRNA synthesis. Polymorphisms can influence mRNAs stability and genes expression, and hence affect the binding of miRNAs. Thus, the present study evaluated the association of DROSHA and DICER1 polymorphisms in the development of endometriosis and other diseases. METHODS: A total of 240 endometriosis cases and 242 controls were genotyped...
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