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Article

Childhood trauma, life-time self-harm, and suicidal behaviour and ideation are associated with polygenic scores for autism.

Molecular psychiatry - 1 May 2021

Warrier Varun, Baron-Cohen Simon

Abstract excerpt

Autistic individuals experience significantly elevated rates of childhood trauma, self-harm and suicidal behaviour and ideation (SSBI). Is this purely the result of negative environmental experiences, or does this interact with genetic predisposition? In this study we investigated if a genetic predisposition for autism is associated with childhood trauma using polygenic scores (PGS) and genetic correlations in...

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Identifiers

PMID: 31659270
DOI: 10.1038/s41380-019-0550-x
PMCID: PMC8159746

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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