Article
TGFβ-like DAF-7 acts as a systemic signal for autophagy regulation in C. elegans.
The Journal of cell biology - 2 Dec 2019
Zhang Yujie, Qi Linxiang, Zhang Hong
Abstract excerpt
In response to stress conditions, autophagy activity in multicellular organisms is systemically modulated to ensure maintenance of cellular homeostasis at an organismal level. Very little is known about the intercellular signals that elicit the long-range organism-wide autophagy response. Here we showed that during Caenorhabditis elegans development, loss of cuticle annular furrow collagens elicits autophagy in...
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