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Article

Shared developmental roles and transcriptional control of autophagy and apoptosis in <i>Caenorhabditis elegans</i>

18 Apr 2011

Abstract excerpt

Autophagy is a lysosome-mediated self-degradation process of eukaryotic cells that, depending on the cellular milieu, can either promote survival or act as an alternative mechanism of programmed cell death (PCD) in terminally differentiated cells. Despite the important developmental and medical implications of autophagy and the main form of PCD, apoptosis, orchestration of their regulation remains poorly...

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PMID: 21502138
DOI: 10.1242/jcs.080192

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