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Article

Gtdap-1 promotes autophagy and is required for planarian remodeling during regeneration and starvation.

Proceedings of the National Academy of Sciences of the United States of America - 14 Aug 2007

González-Estévez Cristina, Felix Daniel A, Aboobaker Aziz A, Saló Emili

Abstract excerpt

Remodeling is an integral component of tissue homeostasis and regeneration. In planarians, these processes occur constantly in a simple tractable model organism as part of the animal's normal life history. Here, we have studied the gene Gtdap-1, the planarian ortholog of human death-associated protein-1 or DAP-1. DAP-1, together with DAP-kinase, has been identified as a positive mediator of programmed cell death...

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Source

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Identifiers

PMID: 17686979
DOI: 10.1073/pnas.0703588104
PMCID: PMC1948951

Genes

DAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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