A novel LRRK2 mutation in a mainland Chinese patient with familial Parkinson's disease.

doi:10.1016/j.neulet.2009.10.080

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Article

A novel LRRK2 mutation in a mainland Chinese patient with familial Parkinson's disease.

Neuroscience letters - 14 Jan 2010

Wang Lei, Guo Ji-feng, Nie Li-luo, Xu Qian, Zuo Xing, Sun Qi-ying, Yan Xin-xiang, Tang Bei-sha

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are known to cause typical, late-onset familial Parkinson's disease in different geographic origins. However, there was no report about mutations of LRRK2 gene in mainland China. The 51 coding exons and intron/exon boundaries of the LRRK2...

Topics

Adult
Aged
Asian People
China
Female
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Male
Middle Aged
Mutation
Parkinson Disease
Pedigree
Protein Serine-Threonine Kinases

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