Article
Human amniotic fluid stem cells attract osteoprogenitor cells in bone healing.
Journal of cellular physiology - 1 May 2020
Basile Mariangela, Marchegiani Francesco, Novak Sanja, Kalajzic Ivo, Di Pietro Roberta
Abstract excerpt
Current treatments of large bone defects are based on autologous or allogenic bone transplantation. Human amniotic fluid stem cells (hAFSCs) were evaluated for their potential in bone regenerative medicine. In this study, hAFSCs were transduced with lentiviral vector harboring red fluorescent protein to investigate their role in the regeneration of critical-size bone defects in calvarial mouse model. To...
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