Article
Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780,000 participants.
Molecular psychiatry - 1 Apr 2021
Rosoff Daniel B, Clarke Toni-Kim, Adams Mark J, McIntosh Andrew M, Davey Smith George, Jung Jeesun, Lohoff Falk W
Abstract excerpt
Observational studies suggest that lower educational attainment (EA) may be associated with risky alcohol use behaviors; however, these findings may be biased by confounding and reverse causality. We performed two-sample Mendelian randomization (MR) using summary statistics from recent genome-wide association studies (GWAS) with >780,000 participants to assess the causal effects of EA on alcohol use behaviors and...
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