Article
Association between oestrogen receptors and female temporomandibular disorders.
Acta odontologica Scandinavica - 1 Apr 2020
Küchler Erika Calvano, Meger Michelle Nascimento, Ayumi Omori Marjorie, Gerber Jennifer Tsi, Carneiro Martins Neto Evandro, Silva Machado Nilza Cristina da, Cavalcante Rafael Corrêa, Teixeira Lucas Ribeiro, Stuani Maria Bernadete, Nelson Filho Paulo, da Costa Delson João, Souza Juliana Feltrin de, Brancher João Armando, León Jorge Esquiche, Scariot Rafaela
Abstract excerpt
Objective: To evaluate if temporomandibular disorders (TMDs) are associated with genetic polymorphisms in ESR1 and ESR2, which are genes encoding oestrogen receptor alpha (ERα) and beta (ERβ). Also, we included an animal model to check if ERα and ERβ are expressed in the temporomandibular joint (TMJ) during adolescence.Materials and methods: A total of 139 teenagers and 93 adults were diagnosed according to the...
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