Mendelian randomization study showed no causality between metformin use and lung cancer risk

Abstract excerpt

With its high incidence and mortality, lung cancer is a heavy burden on public health.1 Prevention of lung cancer is of great importance. There have been reports of reduced lung cancer incidence after use of metformin.2,3 However, previous reports were based on observational studies, which can be biased by confounders, inverse causality and so on. It remains uncertain whether the observed decreased lung cancer...

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