Article
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium.
International journal of epidemiology - 1 Feb 2020
Kapoor Pooja Middha, Lindström Sara, Behrens Sabine, Wang Xiaoliang, Michailidou Kyriaki, Bolla Manjeet K, Wang Qin, Dennis Joe, Dunning Alison M, Pharoah Paul D P, Schmidt Marjanka K, Kraft Peter, García-Closas Montserrat, Easton Douglas F, Milne Roger L, Chang-Claude Jenny
Abstract excerpt
BACKGROUND: Previous gene-environment interaction studies of breast cancer risk have provided sparse evidence of interactions. Using the largest available dataset to date, we performed a comprehensive assessment of potential effect modification of 205 common susceptibility variants by 13 established breast cancer risk factors, including replication of previously reported interactions. METHODS: Analyses were...
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