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Characterization of Parkinson’s disease using blood-based biomarkers: A multicohort proteomic analysis

11 Oct 2019

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of individuals with PD for diagnostic confirmation and prediction of progression. METHODS AND FINDINGS: In 141 plasma samples (96 PD, 45 neurologically normal control [NC]...

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PMID: 31603904
DOI: 10.1371/journal.pmed.1002931

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