Alcohol and aldehyde dehydrogenase isoenzymes in North American Indians.

doi:10.1111/j.1530-0277.1985.tb05540.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Alcohol and aldehyde dehydrogenase isoenzymes in North American Indians.

Alcoholism, clinical and experimental research - 1 Jan 2000

Rex D K, Bosron W F, Smialek J E, Li T K

Abstract excerpt

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) isoenzyme phenotypes were determined in autopsy liver samples from 50 North American Indians from New Mexico. Forty-six of the 50 livers had sufficient ADH activity to allow phenotyping at the ADH2 and ADH3 loci. All 46 livers possessed the "typical" ADH2 1-1 phenotype. The frequency of the ADH3(2) allele was 0.59 and is the highest thus far reported...

Topics

Adolescent
Adult
Aged
Alcohol Dehydrogenase
Alcohol Oxidoreductases
Aldehyde Dehydrogenase
Child
Child, Preschool
Female
Humans
Indians, North American
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isoenzymes

Male

Middle Aged

New Mexico

Phenotype

Racial Groups

Source

Open in PubMed

Identifiers

PMID: 3159308
DOI: 10.1111/j.1530-0277.1985.tb05540.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3159308-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alcohol and aldehyde dehydrogenase isoenzymes in North American Indians.PMID 3159308Read ↗

ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans.Semantic proximity Read ↗

Alcohol dehydrogenase: enzymology and metabolism.Semantic proximity Read ↗

Molecular genetics of human aldehyde dehydrogenase.Semantic proximity Read ↗

Alcohol dehydrogenase polymorphisms in Native Americans: identification of the ADH2*3 allele.Semantic proximity Read ↗

Variations in ADH and ALDH in Southwest California Indians.Semantic proximity Read ↗

Aldehyde dehydrogenase (ALDH) isozymes in the gray short-tailed opossum (Monodelphis domestica): tissue and subcellular distribution and biochemical genetics of ALDH3.Semantic proximity Read ↗

Variations in alcohol-metabolizing enzymes in people of East Indian and African descent from Trinidad and Tobago.Semantic proximity Read ↗

Distribution of ADH2 and ALDH2 genotypes in different populations.Semantic proximity Read ↗

Mitochondrial aldehyde dehydrogenase polymorphism in Asian and American Indian populations: detection of new ALDH2 alleles.Semantic proximity Read ↗

Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human pancreas: implications for pathogenesis of alcohol-induced pancreatic injury.Semantic proximity Read ↗

Population genetic and family studies on aldehyde dehydrogenase deficiency and alcohol sensitivity.Semantic proximity Read ↗

Alcohol dehydrogenase isoenzymes nomenclature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.