Article
Alcohol and aldehyde dehydrogenase isoenzymes in North American Indians.
Alcoholism, clinical and experimental research - 1 Jan 2000
Rex D K, Bosron W F, Smialek J E, Li T K
Abstract excerpt
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) isoenzyme phenotypes were determined in autopsy liver samples from 50 North American Indians from New Mexico. Forty-six of the 50 livers had sufficient ADH activity to allow phenotyping at the ADH2 and ADH3 loci. All 46 livers possessed the "typical" ADH2 1-1 phenotype. The frequency of the ADH3(2) allele was 0.59 and is the highest thus far reported...
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