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Variants in oxidative stress-related genes affect the chemosensitivity through Nrf2-mediated signaling pathway in biliary tract cancer

1 Oct 2019

Abstract excerpt

BACKGROUND: Oxidative stress and their effectors play critical roles in carcinogenesis and chemoresistance. However, the role of oxidative stress-related genes variants in biliary tract cancer (BTC) chemoresistance remains unknown. In this work, we aim to investigate oxidative stress-dependent molecular mechanisms underlying chemoresistance, and find potential biomarkers to predict chemotherapy response for BTC....

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Genomics, phytochemicals, and oxidative stress
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PMID: 31590928
DOI: 10.1016/j.ebiom.2019.08.037

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