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Article

Genomic profile concordance between pancreatic cyst fluid and neoplastic tissue

28 Sept 2019

Abstract excerpt

BACKGROUND: DNA mutational analysis of pancreatic cystic fluid (CF) is a useful adjunct to the evaluation of pancreatic cysts. KRAS/GNAS or RAF/PTPRD/CTNNB1/RNF43 mutations are highly specific to precancerous or advanced neoplasia. Several studies recently demonstrated the ability of next-generation sequencing (NGS) analysis to detect DNA mutations in pancreatic CF, but few studies have performed a systematic...

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PMID: 31576098
DOI: 10.3748/wjg.v25.i36.5530

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