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Epigenetic transgenerational inheritance of testis pathology and Sertoli cell epimutations: generational origins of male infertility

1 Jul 2019

Abstract excerpt

Male reproductive health has been in decline for decades with dropping sperm counts and increasing infertility, which has created a significant societal and economic burden. Between the 1970s and now, a general decline of over 50% in sperm concentration has been observed in the population. Environmental toxicant-induced epigenetic transgenerational inheritance has been shown to affect testis pathology and sperm...

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PMID: 31528361
DOI: 10.1093/eep/dvz013

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