Article
Epigenetic Transgenerational Inheritance of Altered Sperm Histone Retention Sites.
Scientific reports - 28 Mar 2018
Ben Maamar Millissia, Sadler-Riggleman Ingrid, Beck Daniel, Skinner Michael K
Abstract excerpt
A variety of environmental toxicants and factors have been shown to induce the epigenetic transgenerational inheritance of disease and phenotypic variation. Epigenetic alterations in the germline (sperm or egg) are required to transmit transgenerational phenotypes. The current study was designed to investigate the potential role of histones in sperm to help mediate the epigenetic transgenerational inheritance....
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