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Article

Dental caries vaccine: are we there yet?

13 Sept 2019

Abstract excerpt

Abstract Dental caries, caused by Streptococcus mutans, is a common infection. Caries vaccine has been under investigation for the last 40 years. Many in vitro and in vivo studies and some human clinical trials have determined many pertinent aspects regarding vaccine development. The virulence determinants of Strep. mutans, such as Ag I/II, responsible for adherence to surfaces, glucosyltransferase, responsible...

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PMID: 31518435
DOI: 10.1111/lam.13218

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