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The molecular clock of Mycobacterium tuberculosis

12 Sept 2019

Abstract excerpt

The molecular clock and its phylogenetic applications to genomic data have changed how we study and understand one of the major human pathogens, Mycobacterium tuberculosis (MTB), the etiologic agent of tuberculosis. Genome sequences of MTB strains sampled at different times are increasingly used to infer when a particular outbreak begun, when a drug-resistant clone appeared and expanded, or when a strain was...

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PMID: 31513651
DOI: 10.1371/journal.ppat.1008067

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