Article
In utero exposure to maternal diabetes impairs nephron progenitor differentiation.
American journal of physiology. Renal physiology - 1 Nov 2019
Cerqueira Débora M, Hemker Shelby L, Bodnar Andrew J, Ortiz Daniella M, Oladipupo Favour O, Mukherjee Elina, Gong Zhenwei, Appolonia Corynn, Muzumdar Radhika, Sims-Lucas Sunder, Ho Jacqueline
Abstract excerpt
The incidence of diabetes mellitus has significantly increased among women of childbearing age, and it has been shown that prenatal exposure to maternal diabetes increases the risk of associated congenital anomalies of the kidney. Congenital anomalies of the kidney are among the leading causes of chronic kidney disease in children. To better understand the effect of maternal diabetes on kidney development, we...
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