Article
Genetic profiling of azoospermic men to identify the etiology and predict reproductive potential.
Journal of assisted reproduction and genetics - 1 Apr 2024
Cheung Stephanie, Ng Lily, Xie Philip, Kocur Olena, Elias Rony, Schlegel Peter, Rosenwaks Zev, Palermo Gianpiero D
Abstract excerpt
PURPOSE: To identify germline mutations related to azoospermia etiology and reproductive potential of surgically retrieved spermatozoa, and to investigate the feasibility of predicting seminiferous tubule function of nonobstructive azoospermic men by transcriptomic profiling of ejaculates. MATERIALS AND METHODS: Sperm specimens were obtained from 30 men (38.4 ± 6 years) undergoing epididymal sperm aspiration for...
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