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RNAi screening of uncharacterized genes identifies promising druggable targets in Schistosoma japonicum

28 Mar 2025

Abstract excerpt

Schistosomiasis affects more than 250 million people worldwide and is one of the neglected tropical diseases. Currently, the treatment of schistosomiasis relies on a single drug-praziquantel-which has led to increasing pressure from drug resistance. Therefore, there is an urgent need to find new treatments. The development of genome sequencing has provided valuable information for understanding the biology of...

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PMID: 40153463
DOI: 10.1371/journal.ppat.1013014

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