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Article

Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer

21 Aug 2019

Abstract excerpt

We present the functional characterization of a pseudogene associated recurrent gene fusion in prostate cancer. The fusion gene KLK4-KLKP1 is formed by the fusion of the protein coding gene KLK4 with the noncoding pseudogene KLKP1. Screening of a cohort of 659 patients (380 Caucasian American; 250 African American, and 29 patients from other races) revealed that the KLK4-KLKP1 is expressed in about 32% of...

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PMID: 31446281
DOI: 10.1016/j.neo.2019.07.010

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