The relationship between HLA-B*51 subtypes, clinical manifestations and severity of Behçet’s syndrome: a large Italian cohort study

Abstract excerpt

Abstract Objectives Behçet’s syndrome (BS) is a chronic multisystemic inflammatory disorder of unclear aetiology. The predominant BS susceptibility locus was identified within HLA-B*51. HLA-B*51 subtypes were previously studied as disease susceptibility markers. Few data are now available about the relationship between B*51 subtypes and clinical phenotype. The aim of this study was to genotype HLA-B*51 subtypes...

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