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Article

Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling

7 Aug 2019

Abstract excerpt

The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node that has been identified involves p38 MAPK; a family of kinases activated in response to stress and inflammatory stimuli that modulates multiple aspects of cardiac...

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PMID: 31394846
DOI: 10.3390/jcdd6030027

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