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Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues

18 Nov 2022

Abstract excerpt

Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but also impact tissues proximal and distal to the irradiated site. Unveiling the molecular events governing the diverse effects of IR at the cellular and organismal levels is relevant for both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36421472
DOI: 10.3390/antiox11112286

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