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Diagnosis and management of glucokinase monogenic diabetes in pregnancy: current perspectives

1 Jul 2019

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Abstract: Glucokinase–maturity-onset diabetes of the young (GCK-MODY) is an autosomal dominant disorder caused by heterozygous inactivating GCK gene mutations. GCK-MODY is one the most common MODY subtypes, affecting 0.1% of the population and 0.4–1% of women with gestational diabetes mellitus. Glucokinase is predominantly expressed in pancreatic beta cells and catalyzes the phosphorylation of glucose to...

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PMID: 31372018
DOI: 10.2147/dmso.s186610

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Diagnosis and management of glucokinase monogenic diabetes in pregnancy: current perspectivesPMID 31372018Read ↗

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