Article
Aspirin enhances trophoblast invasion and represses soluble fms-like tyrosine kinase 1 production
21 Jul 2019
Abstract excerpt
OBJECTIVE: Recent studies suggested that prophylactic aspirin prior to 16 weeks of gestation in high-risk patients may reduce the risk of developing preeclampsia; however, the exact mechanism of aspirin's effect on the pathophysiology of preeclampsia is not clear. This study was designed to investigate the effect of aspirin on trophoblast cell function and its effect on soluble fms-like tyrosine kinase 1 (sFlt-1)...
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