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Article

RNA editing blood biomarkers for predicting mood alterations in HCV patients

22 Jul 2019

Abstract excerpt

Treatment-emergent depression is a common complication in patients with chronic hepatitis C virus (HCV) infection undergoing antiviral combination therapy with IFN-α and ribavirin. It has recently been shown that changes in A-to-I RNA editing rates are associated with various pathologies such as inflammatory disorders, depression and suicide. Interestingly, IFN-α induces gene expression of the RNA editing enzyme...

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PMID: 31332697
DOI: 10.1007/s13365-019-00772-9

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