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Organoid-based epithelial to mesenchymal transition (OEMT) model: from an intestinal fibrosis perspective

22 May 2017

Abstract excerpt

The current in vitro or in vivo intestinal fibrosis models have many limitations. Recent advancements in the isolation and culturing of organoids has led to development of various three-dimensional (3D) intestinal disease models with in vivo physiology. In this study, we generated an organoid-based epithelial to mesenchymal transition (OEMT) model, which could be used as a novel intestinal fibrosis model....

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PMID: 28550311
DOI: 10.1038/s41598-017-02190-5

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