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A Histone Acetyltransferase Inhibitor with Antifungal Activity against CTG clade Candida Species

15 Jul 2019

Abstract excerpt

Candida species represent one of the most frequent causes of hospital-acquired infections in immunocompromised patient cohorts. Due to a very limited set of antifungals available and an increasing prevalence of drug resistance, the discovery of novel antifungal targets is essential. Targeting chromatin modifiers as potential antifungal targets has gained attention recently, mainly due to their role in regulating...

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PMID: 31311209
DOI: 10.3390/microorganisms7070201

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