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Article

Cytokine Selection of MSC Clones with Different Functionality

11 Jul 2019

Abstract excerpt

Mesenchymal stromal cells (MSCs) are used in many clinical applications. However, ex vivo expansion is required to reach clinically relevant cell numbers, which might lead to selection of clones with different characteristics. To follow clonal selection, we transduced MSC progenitors in umbilical cord pieces (UCPs) with vectors encoding fluorescent proteins and genetic barcodes. After marked MSC cultures grew out...

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PMID: 31303506
DOI: 10.1016/j.stemcr.2019.06.001

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