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The effects of CRISPR-Cas9 knockout of the TGF-β1 gene on antler cartilage cells in vitro

22 Jun 2019

Abstract excerpt

BACKGROUND: Deer antler is the only mammalian organ that can be completely regenerated every year. Its periodic regeneration is regulated by multiple factors, including transforming growth factor β (TGF-β). This widely distributed multi-functional growth factor can control the proliferation and differentiation of many types of cell, and it may play a crucial regulatory role in antler regeneration. This study...

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PMID: 31285745
DOI: 10.1186/s11658-019-0171-z

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