Article
Integrated multi-omics analysis of genomics, epigenomics, and transcriptomics in ovarian carcinoma
29 Jun 2019
Abstract excerpt
In this study, we identified prognostic biomarkers in ovarian carcinoma by integrating multi-omics DNA copy number variation (CNV) and methylation variation (MET) data. CNV, MET, and messenger RNA (mRNA) expression were examined in 351 ovarian carcinoma patients. Genes for which expression was correlated with DNA copy-number or DNA methylation were identified; three ovarian carcinoma gene subtypes were defined...
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