Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long non-coding RNA HAND2-AS1 downregulation predicts poor survival of patients with end-stage dilated cardiomyopathy

27 Jun 2019

Abstract excerpt

Objective Insulin-like growth factor-1 (IGF-1) signaling is inhibited in end-stage dilated cardiomyopathy (DCM), and recombinant IGF-1 improves cardiac function in DCM patients. Long non-coding (lnc)RNA HAND2-AS1 was previously shown to be involved in cancer development, but its role in DCM is unknown. The present study investigated the involvement of IGF-1 and HAND2-AS1 in DCM. Methods Plasma HAND2-AS1 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cardiac Valve Diseases and Treatments
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31248315
DOI: 10.1177/0300060519849295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long non-coding RNA HAND2-AS1 downregulation predicts poor survival of patients with end-stage dilated cardiomyopathyPMID 31248315Read ↗

The role of long non-coding RNAs in cardiovascular diseases: A comprehensive reviewSemantic proximity Read ↗

Identification of cardiac long non-coding RNA profile in human dilated cardiomyopathy.Semantic proximity Read ↗

Circulating Long Non-coding RNA ENST00000507296 Is a Prognostic Indicator in Patients with Dilated CardiomyopathySemantic proximity Read ↗

Long noncoding RNA in cardiac aging and diseaseSemantic proximity Read ↗

Downregulation of AC061961.2, LING01-AS1, and RP11-13E1.5 is associated with dilated cardiomyopathy progression.Semantic proximity Read ↗

Differential expression profiles of plasma exosomal microRNAs in dilated cardiomyopathy with chronic heart failureSemantic proximity Read ↗

The role and medical prospects of long non-coding RNAs in cardiovascular diseaseSemantic proximity Read ↗

Research Progress of Exosomal Non-Coding RNAs in Cardiac RemodelingSemantic proximity Read ↗

FIMICS: A panel of long noncoding RNAs for cardiovascular conditionsSemantic proximity Read ↗

Long noncoding RNA dysregulation in ischemic heart failureSemantic proximity Read ↗

RNA binding protein IGF2BP2 expression is induced by stress in the heart and mediates dilated cardiomyopathySemantic proximity Read ↗

Mitochondrial long noncoding RNAs as blood based biomarkers for cardiac remodeling in patients with hypertrophic cardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.