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Article

Drosophila melanogaster as a model to study virulence and azole treatment of the emerging pathogen Candida auris

28 Mar 2019

Abstract excerpt

OBJECTIVES: Candida auris is an emerging, often MDR, yeast pathogen. Efficient animal models are needed to study its pathogenicity and treatment. Therefore, we developed a C. auris fruit fly infection model. METHODS: TollI-RXA/Tollr632 female flies were infected with 10 different C. auris strains from the CDC Antimicrobial Resistance bank panel. We used three clinical Candida albicans strains as controls. For...

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PMID: 31225606
DOI: 10.1093/jac/dkz100

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