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Article

Megaesophagus Is a Major Pathological Condition in Rats With a Large Deletion in the Rbm20 Gene.

Veterinary pathology - 1 Jan 2020

Schwahn Denise J, Pleitner Jonathan M, Greaser Marion L

Abstract excerpt

A spontaneously arising, loss-of-function mutation in the RNA binding motif protein 20 (Rbm20) gene, which encodes a nuclear splicing protein, was previously identified as the underlying reason for expression of an abnormally large TITIN (TTN) protein in a rat model of cardiomyopathy. An outbreak of Pseudomonas aeruginosa led to submission of rats with dyspnea, sneezing, lethargy, nasal discharge, and/or...

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Source

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Identifiers

PMID: 31221019
DOI: 10.1177/0300985819854224
PMCID: PMC7221460

Genes

TTN
RBM20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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