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Article

Systems analysis of subjects acutely infected with the Chikungunya virus

18 Jun 2019

Abstract excerpt

The largest ever recorded epidemic of the Chikungunya virus (CHIKV) broke out in 2004 and affected four continents. Acute symptomatic infections are typically associated with the onset of fever and often debilitating polyarthralgia/polyarthritis. In this study, a systems biology approach was adopted to analyze the blood transcriptomes of adults acutely infected with the CHIKV. Gene signatures that were associated...

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PMID: 31211814
DOI: 10.1371/journal.ppat.1007880

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