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Article

BRCA2 deficiency is a potential driver for human primary ovarian insufficiency

17 Jun 2019

Abstract excerpt

Abstract Reproductive problem has been one of the top issues for women health worldwide in recent decades. As a typical female disease, primary ovarian insufficiency (POI) results in a loss of ovarian follicles and oocytes that thus destroys women fertility. However, due to the complex of POI etiology and rare resource of human POI oocytes, few biomarkers have been identified in clinics and no effective strategy...

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PMID: 31209201
DOI: 10.1038/s41419-019-1720-0

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