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Article

Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma

11 Jun 2019

Abstract excerpt

BACKGROUND: Using a pathway-focused approach, we aimed to provide a subgroup-specific basis for finding novel therapeutic strategies and further refinement of the risk stratification in pediatric medulloblastoma. METHOD: Based on genome-wide Cox regression and Gene Set Enrichment Analysis, we investigated prognosis-related signaling pathways and core genes in pediatric medulloblastoma subgroups using 530 patient...

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PMID: 31185958
DOI: 10.1186/s12885-019-5742-x

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