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Article

Immune System and DNA Repair Defects in Ovarian Cancer: Implications for Locoregional Approaches

25 May 2019

Abstract excerpt

In the last few years, substantial progress has been made in the treatment of ovarian cancer, with increased knowledge about the biology of the disease. Ovarian cancer is a neoplasm strongly linked to defects in DNA repair mechanisms, where deficiency in the homologous recombination (HR) system results in a better response of ovarian cancers to therapy, whether platinum-based chemotherapy, anthracyclines, or poly...

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PMID: 31130614
DOI: 10.3390/ijms20102569

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