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Germline and Somatic Mutations in Prostate Cancer for the Clinician

1 May 2019

Abstract excerpt

It is increasingly important for clinicians involved in the management of prostate cancer to understand the relevance of heritable (germline) mutations that, for select patients, affect prostate cancer risk and cancer biology, and acquired (somatic) mutations that occur in prostate cancer cells. In the advanced disease setting, mutations in homologous recombination repair genes (eg, BRCA1, BRCA2, ATM, CHEK2,...

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PMID: 31085765
DOI: 10.6004/jnccn.2019.7307

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