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Overexpression of chaperonin containing T-complex polypeptide subunit zeta 2 (CCT6b) suppresses the functions of active fibroblasts in a rat model of joint contracture

9 May 2019

Abstract excerpt

BACKGROUND: Joint contracture is a fibrous disease characterized as joint capsule fibrosis that results in joint dysfunction and disability. The purpose of this study was to analyze the biological activities of chaperonin containing T-complex polypeptide (CCT) subunits and to determine the role of CCT chaperone in joint contracture in a rat model. METHODS: In this study, the rat model of joint contracture was...

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PMID: 31072365
DOI: 10.1186/s13018-019-1161-6

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